QR-Code

HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway

Background: HIV infection dysregulates the B cell compartment, affecting memory B cell formation and the antibody response to infection and vaccination. Understanding the B cell response to SARS-CoV-2 in people living with HIV (PLWH) may explain the increased morbidity, reduced vaccine efficacy, red...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Robert Krause, Jumari Snyman, Hwa Shi-Hsia, Daniel Muema, Farina Karim, Yashica Ganga, Abigail Ngoepe, Yenzekile Zungu, Inbal Gazy, Mallory Bernstein, Khadija Khan, Matilda Mazibuko, Ntombifuthi Mthabela, Dirhona Ramjit, COMMIT-KZN Team, Oliver Limbo, Joseph Jardine, Devin Sok, Ian A Wilson, Willem Hanekom, Alex Sigal, Henrik Kløverpris, Thumbi Ndung'u, Alasdair Leslie
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2022-10-01
Schriftenreihe:eLife
Schlagworte:
COVID-19
SARS-CoV-2
HIV
B cell
spike
RBD
Online-Zugang:https://elifesciences.org/articles/79924
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge