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LncRNA H19 Suppresses Osteosarcomagenesis by Regulating snoRNAs and DNA Repair Protein Complexes

Osteosarcoma is one of the most frequent common primary malignant tumors in childhood and adolescence. Long non-coding RNAs (lncRNAs) have been reported to regulate the initiation and progression of tumors. However, the exact molecular mechanisms involving lncRNA in osteosarcomagenesis remain largel...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: An Xu, Mo-Fan Huang, Dandan Zhu, Julian A. Gingold, Danielle A. Bazer, Betty Chang, Donghui Wang, Chien-Chen Lai, Ihor R. Lemischka, Ruiying Zhao, Dung-Fang Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-01-01
Schriftenreihe:Frontiers in Genetics
Schlagworte:
osteosarcoma
H19 lncRNA
iPSCs
Li-Fraumeni syndrome
snoRNA
p53
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fgene.2020.611823/full
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