Curcumin's Protective Role in Heatstroke‐Induced Acute Liver Injury: Targeting Pyroptosis and Enhancing SIRT1 Expression

Abstract Heatstroke (HS) is a severe systemic condition that significantly impacts organ function, with the liver being particularly vulnerable. Sirtuin 1 (SIRT1), a crucial deacetylase, is implicated in various diseases' pathophysiology. Curcumin, a natural polyphenol, has been shown to modulate SI...

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Главные авторы:	Yizhan Wu, Fei Guo, Yan Ma, Weihao Chai, Jiajia Li, Wenhui Shi, Jiangwei Liu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2024-12-01
Серии:	Global Challenges
Предметы:	acute liver injury curcumin heatstroke pyroptosis SIRT1
Online-ссылка:	https://doi.org/10.1002/gch2.202400178
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