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Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis.

Inflammatory bowel disease (IBD) is chronic inflammation of the gastrointestinal tract that affects millions of people worldwide. Although the etiology of IBD is not clear, it is known that products from stressed cells and enteric microbes promote intestinal inflammation. High mobility group box 1 (...

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Bibliografiska uppgifter
Huvudupphov: Zhongliang Ju, Sangeeta S Chavan, Daniel J Antoine, Meghan Dancho, Teá Tsaava, Jianhua Li, Ben Lu, Yaakov A Levine, Andrew Stiegler, Yehuda Tamari, Yousef Al-Abed, Jesse Roth, Kevin J Tracey, Huan Yang
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC4134190?pdf=render
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