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Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing

Abstract Background Circular RNAs (circRNAs) contribute to multiple biological functions and are also involved in pathological conditions such as cancer. However, the role of circRNAs in metabolic reprogramming, especially upon energy stress in lung adenocarcinoma (LUAD), remains largely unknown. Me...

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Hlavní autoři: Zhifei Ma, Hao Chen, Zhijun Xia, Jing You, Chencheng Han, Siwei Wang, Wenjia Xia, Yongkang Bai, Tongyan Liu, Lin Xu, Guoren Zhou, Youtao Xu, Rong Yin
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2023-07-01
Edice:Journal of Experimental & Clinical Cancer Research
Témata:
Energy stress
circRNA
Lung adenocarcinoma
Oxidative phosphorylation
Alternative splicing.
On-line přístup:https://doi.org/10.1186/s13046-023-02723-z
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