BMP-2 gene-modified mesenchymal stem cells enhance tendon–bone healing in ACL reconstruction: a rabbit micro-CT and biomechanical study

Abstract Objective Suboptimal tendon-bone interface healing remains a critical challenge affecting outcomes of anterior cruciate ligament (ACL) reconstruction. This study investigates whether BMP-2 gene-modified bone marrow mesenchymal stem cells (MSCs) enhances tendon-bone osseointegration. Methods...

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Principais autores:	Hongcheng Zheng, Yongtao Zeng, Nacke Daoerji, Husen Wang, Bin Tang, Li Shu
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-11-01
Serija:	BMC Surgery
Teme:	Anterior cruciate ligament reconstruction Bone marrow mesenchymal stem cells Bone morphogenetic protein-2 Tendon-Bone interface Gene modification
Online dostop:	https://doi.org/10.1186/s12893-025-03277-x
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