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Synthesis, Characterization and Preliminary Anticancer Study of Novel 5-fluorouracil Conjugate with Pyrrolidine Dithiocarbamate as a Mutual Anticancer Prodrug

 5-Fluorouracil is one of the commonly used chemotherapy drugs in anticancer therapy; unfortunately treatment with 5-FU by solely has many drawbacks  low lipophilicity, low permeability, low molecular weight, and its relatively poor plasma protein binding; also a brief half-life therefore frequent...

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Autors principals: Ikram K. Shihab, Mohammed H. Mohammed
Format: Artigo
Idioma:Inglês
Publicat: College of Pharmacy University of Baghdad 2019-12-01
Col·lecció:Iraqi Journal of Pharmaceutical Sciences
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Accés en línia:https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/874
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