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Revised therapeutic window for vancomycin in pediatric patients: evidence from a retrospective therapeutic drug monitoring study

Abstract Objective Methicillin-resistant Staphylococcus aureus (MRSA) infections among children are escalating annually. Vancomycin serves as the frontline therapeutic agent against MRSA infections. However, determining the therapeutic window that maximizes efficacy while minimizing the risk of toxi...

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Principais autores: Tao Zhang, Jingjing Yi, Hua Cheng, Xinyan Han, Yan Wang, Jiao Xie, Qianting Yang, Sasa Hu, Yalin Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-11-01
coleção:BMC Pharmacology and Toxicology
Assuntos:
Vancomycin
Pediatrics
Therapeutic drug monitoring
Therapeutic window
Pharmacodynamics
Acesso em linha:https://doi.org/10.1186/s40360-025-01035-6
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