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Agents that affect cAMP levels or protein kinase A activity modulate memory consolidation when injected into rat hippocampus but not amygdala

Male Wistar rats were trained in one-trial step-down inhibitory avoidance using a 0.4-mA footshock. At various times after training (0, 1.5, 3, 6 and 9 h for the animals implanted into the CA1 region of the hippocampus; 0 and 3 h for those implanted into the amygdala), these animals received microin...

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Wedi'i Gadw mewn:
Prif Awduron: L. Bevilaqua, P. Ardenghi, N. Schröder, E. Bromberg, J. Quevedo, P.K. Schmitz, M. Bianchin, R. Walz, E. Schaeffer, J.H. Medina, I. Izquierdo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Associação Brasileira de Divulgação Científica 1997-08-01
Cyfres:Brazilian Journal of Medical and Biological Research
Pynciau:
memory formation
memory modulation
hippocampus
amygdala
cAMP/PKA/CREB-P pathway
dopamine D
receptors
ß-adrenoceptors
5HT1A receptors
Mynediad Ar-lein:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800009
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