Randomized Controlled Preclinical Trial of a Benzodiazepine–Dihydropyridine Hybrid Molecule in Rodent Stroke

Background The 3‐ethoxycarbonyl‐2‐methyl‐4‐(2‐nitrophenyl)‐4,11‐dihydro‐1H‐pyrido[2,3‐b][1,5]benzodiazepine (JM‐20) molecule is a novel multifunctional molecule with potent neuroprotective effects in rat focal cerebral ischemia. To confirm previous results obtained in single laboratories with small...

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Prif Awduron:	Jeney Ramírez‐Sánchez, André Rex, Sarah K. McCann, Daniel Schulze, Maylin Wong‐Guerra, Luis A. Fonseca‐Fonseca, Enrique García‐Alfonso, Ailín Ramírez‐Abreu, Ricardo Limonta, Monika Dopatka, Larissa Mosch, Yanier Núñez‐Figueredo, Ulrich Dirnagl
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Wiley 2025-08-01
Cyfres:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Pynciau:	ischemic stroke middle cerebral artery occlusion mouse neuroprotection rat
Mynediad Ar-lein:	https://www.ahajournals.org/doi/10.1161/JAHA.124.040621
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