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Screening of active components in Astragalus mongholicus Bunge and Panax notoginseng formula for anti-fibrosis in CKD: nobiletin inhibits Lgals1/PI3K/AKT signaling to improve renal fibrosis

The Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) has been clinically shown to effectively slow down the progression of chronic kidney disease (CKD) and has demonstrated significant anti-fibrosis effects in experimental CKD model. However, the specific active ingredients and under...

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Principais autores: Fang Yang, Tong Li, Xiao-qian Zhang, Yi Gong, Hongwei Su, Junming Fan, Li Wang, Qiong-dan Hu, Rui-zhi Tan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:Renal Failure
Assuntos:
Nobiletin
renal fibrosis
Lgals1
PI3K/AKT
chronic kidney disease
Acesso em linha:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2375033
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