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Expression of CCCTC‐binding factor (CTCF) is linked to poor prognosis in prostate cancer

The chromatin‐organizing factor CCCTC‐binding factor (CTCF) is involved in transcriptional regulation, DNA‐loop formation, and telomere maintenance. To evaluate the clinical impact of CTCF in prostate cancer, we analyzed CTCF expression by immunohistochemistry on a tissue microarray containing 17 74...

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Principais autores: Doris Höflmayer, Amélie Steinhoff, Claudia Hube‐Magg, Martina Kluth, Ronald Simon, Eike Burandt, Maria Christina Tsourlakis, Sarah Minner, Guido Sauter, Franziska Büscheck, Waldemar Wilczak, Stefan Steurer, Hartwig Huland, Markus Graefen, Alexander Haese, Hans Heinzer, Thorsten Schlomm, Frank Jacobsen, Andrea Hinsch, Alexandra M. Poos, Marcus Oswald, Karsten Rippe, Rainer König, Cornelia Schroeder
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2020-01-01
Serier:Molecular Oncology
Fag:
CTCF
deletion
prostate cancer
TMA
Online adgang:https://doi.org/10.1002/1878-0261.12597
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