Lipoproteins LDL versus HDL as nanocarriers to target either cancer cells or macrophages

In this work, we have explored natural unmodified low- and high-density lipoproteins (LDL and HDL, respectively) as selective delivery vectors in colorectal cancer therapy. We show in vitro in cultured cells and in vivo (NanoSPECT/CT) in the CT-26 mice colorectal cancer model that LDLs are mainly ta...

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मुख्य लेखकों:	Tarik Hadi, Christophe Ramseyer, Thomas Gautier, Pierre-Simon Bellaye, Tatiana Lopez, Antonin Schmitt, Sarah Foley, Semen Yesylevskyy, Thibault Minervini, Romain Douhard, Lucile Dondaine, Lil Proukhnitzky, Samir Messaoudi, Maeva Wendremaire, Mathieu Moreau, Fabrice Neiers, Bertrand Collin, Franck Denat, Laurent Lagrost, Carmen Garrido, Frederic Lirussi
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Clinical investigation 2020-12-01
श्रृंखला:	JCI Insight
विषय:	Oncology Therapeutics
ऑनलाइन पहुंच:	https://doi.org/10.1172/jci.insight.140280
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