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Exploring the Causal Relationship between Ibuprofen Use and Osteoarthritis Risk: A Mendelian Randomization Study

This study explored the potential causal relationship between ibuprofen (IBU) use and the risk of developing osteoarthritis, a prevalent joint disorder characterized by pain and stiffness. We conducted a two-sample MR analysis using four distinct OA GWAS datasets as outcomes and single-nucleotide po...

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Autori principali: Yongzhi Jian, Yanmin Lyu, Said Hashemolhosseini
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-09-01
Serie:Biology
Soggetti:
ibuprofen
osteoarthritis
Mendelian randomization
GWAS
causal inference
Accesso online:https://www.mdpi.com/2079-7737/13/9/748
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