Endothelial glycocalyx degradation is more severe in patients with non-pulmonary sepsis compared to pulmonary sepsis and associates with risk of ARDS and other organ dysfunction

Abstract Background Disruption of the endothelial glycocalyx contributes to acute lung injury in experimental sepsis but has not been well studied in humans. To study glycocalyx degradation in sepsis-induced ARDS, we measured plasma levels of syndecan-1, a marker for glycocalyx degradation. Methods...

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Principais autores:	Laura S. Murphy, Nancy Wickersham, J. Brennan McNeil, Ciara M. Shaver, Addison K. May, Julie A. Bastarache, Lorraine B. Ware
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2017-10-01
叢編:	Annals of Intensive Care
主題:	Syndecan-1 Glycocalyx Sepsis Acute respiratory distress syndrome (ARDS)
在線閱讀:	http://link.springer.com/article/10.1186/s13613-017-0325-y
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