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PEGDA microencapsulated allogeneic islets reverse canine diabetes without immunosuppression.

<h4>Background</h4>Protection of islets without systemic immunosuppression has been a long-sought goal in the islet transplant field. We conducted a pilot biocompatibility/safety study in healthy dogs followed by a dose-finding efficacy study in diabetic dogs using polyethylene glycol diacrylate (PE...

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Autors principals: Stephen Harrington, Francis Karanu, Karthik Ramachandran, S Janette Williams, Lisa Stehno-Bittel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2022-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0267814
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