Hypoxia controls plasma membrane targeting of polarity proteins by dynamic turnover of PI4P and PI(4,5)P2

Phosphatidylinositol 4-phosphate (PI4P) and phosphatidylinositol 4,5-biphosphate (PIP2) are key phosphoinositides that determine the identity of the plasma membrane (PM) and regulate numerous key biological events there. To date, mechanisms regulating the homeostasis and dynamic turnover of PM PI4P...

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Autors principals:	Juan Lu, Wei Dong, Gerald R Hammond, Yang Hong
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2022-06-01
Col·lecció:	eLife
Matèries:	PI4P PI(4,5)P2 PI4KIIIα hypoxia electrostatic membrane targeting polarity
Accés en línia:	https://elifesciences.org/articles/79582
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