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Co-Delivery of 5-Fluorouracil and Paclitaxel in Mitochondria-Targeted KLA-Modified Liposomes to Improve Triple-Negative Breast Cancer Treatment

In this research, KLA-modified liposomes co-loaded with 5-fluorouracil and paclitaxel (KLA-5-FU/PTX Lps) were developed, and their antitumor activity against triple-negative breast cancer (TNBC) was evaluated. KLA-5-FU/PTX Lps were prepared using the thin-film dispersion method, and their in vitro a...

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Hlavní autoři: Tianyu Chen, Hui Chen, Yichun Jiang, Qi Yan, Shuling Zheng, Min Wu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-07-01
Edice:Pharmaceuticals
Témata:
5-fluorouracil
paclitaxel
liposomes
mitochondrial targeting
TNBC
On-line přístup:https://www.mdpi.com/1424-8247/15/7/881
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