Counteracting suppression of CFTR and voltage-gated K+ channels by a bacterial pathogenic factor with the natural product tannic acid

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) cause recurring bacterial infection in CF patients' lungs. However, the severity of CF lung disease correlates poorly with genotype. Antibiotic treatment helps dramatically prolong patients' life. The lung disease generally...

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書誌詳細

主要な著者:	Yajamana Ramu, Yanping Xu, Hyeon-Gyu Shin, Zhe Lu
フォーマット:	Artigo
言語:	Inglês
出版事項:	eLife Sciences Publications Ltd 2014-10-01
シリーズ:	eLife
主題:	potassium channel CFTR phospholipase sphingomyelinase toxin channel inhibition
オンライン･アクセス:	https://elifesciences.org/articles/03683
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