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Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits

OBJECTIVES: Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of choice; however, the progression of retinal lesions ceases approximately 2 days after treatment initiation. An intravitreal injection o...

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Principais autores: Francisco Max Damico, Mariana Ramos Scolari, Gabriela Lourençon Ioshimoto, Beatriz Sayuri Takahashi, Armando da Silva Cunha Jr., Sílvia Ligório Fialho, Daniela Maria Bonci, Fabio Gasparin, Dora Fix Ventura
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier España 2012-08-01
Serier:Clinics
Fag:
Acyclovir
Pharmacokinetics
Electroretinography
Drug Toxicity
Retina
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000800013
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