Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Abstract Background Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnos...

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Detalhes bibliográficos

Principais autores:	Chung-Er Huang, Gwo-Chin Ma, Hei-Jen Jou, Wen-Hsiang Lin, Dong-Jay Lee, Yi-Shing Lin, Norman A. Ginsberg, Hsin-Fu Chen, Frank Mau-Chung Chang, Ming Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-12-01
coleção:	Molecular Cytogenetics
Assuntos:	cbNIPD Aneuploidy fnRBC EVT NIPT Fish
Acesso em linha:	http://link.springer.com/article/10.1186/s13039-017-0343-3
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