Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU

Abstract Background Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. TcII is among the major DTUs enrolled in human infections in South America southern cone, where it is associated with severe cardiac and digestive...

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Autors principals:	João Luís Reis-Cunha, Rodrigo P. Baptista, Gabriela F. Rodrigues-Luiz, Anderson Coqueiro-dos-Santos, Hugo O. Valdivia, Laila Viana de Almeida, Mariana Santos Cardoso, Daniella Alchaar D’Ávila, Fernando Hugo Cunha Dias, Ricardo Toshio Fujiwara, Lúcia M. C. Galvão, Egler Chiari, Gustavo Coutinho Cerqueira, Daniella C. Bartholomeu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-11-01
Col·lecció:	BMC Genomics
Matèries:	Trypanosoma cruzi TcII Field isolates Genomic variability Copy number variation Ploidy
Accés en línia:	http://link.springer.com/article/10.1186/s12864-018-5198-4
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