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Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension

Assembly of the actin cytoskeleton is an important part of formation of neurites in developing neurons. Tropomodulin, a tropomyosin-dependent capping protein for the pointed end of the actin filament, is one of the key players in this process. Tropomodulin binds tropomyosin in two binding sites. Tmo...

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Autors principals: Natalia Moroz, Laurent Guillaud, Brinda Desai, Alla S. Kostyukova
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2013-02-01
Col·lecció:PeerJ
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Accés en línia:https://peerj.com/articles/7.pdf
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