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The role of RICTOR amplification in targeted therapy and drug resistance

Abstract The emergence of tyrosine kinase inhibitors (TKIs) has changed the current treatment paradigm and achieved good results in recent decades. However, an increasing number of studies have indicated that the complex network of receptor tyrosine kinase (RTK) co-activation could influence the cha...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Deze Zhao, Man Jiang, Xiaochun Zhang, Helei Hou
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-02-01
Schriftenreihe:Molecular Medicine
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Online-Zugang:https://doi.org/10.1186/s10020-020-0146-6
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