UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes
The enzyme serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the first committed and rate-limiting step in sphingolipid synthesis, is up-regulated in the epidermis as part of the homeostatic repair in response to permeability barrier perturbation. Moreover, UVB exposure, which also per...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
1998-10-01
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| Serier: | Journal of Lipid Research |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S0022227520325013 |
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