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Autophagy, a novel player in acetaminophen (APAP)-induced hepatotoxicity

Acetaminophen (APAP), a widely used analgesic drug, is safe at therapeutic doses, but can produce significant hepatotoxicity upon overdose. Emerging evidence suggested that endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) are key mechanisms in APAP-mediated hepatotoxicity. W...

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Bibliográfalaš dieđut
Váldodahkkit: Hui Ye, Francisco Javier Cubero
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Taylor & Francis Group 2022-12-01
Ráidu:Autophagy Reports
Fáttát:
Liŋkkat:http://dx.doi.org/10.1080/27694127.2022.2103779
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