Unusually strong temperature dependence of P2X3 receptor traffic to the plasma membrane

ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly enhanced at high temperatures, suggesting a role for these receptors in temperature detection. Since sustained responsiveness depends on receptor traffi...

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Autores principales:	Evgeny ePryazhnikov, Dmitriy eFayuk, Minna eNiittykoski, Rashid eGiniatullin, Leonard eKhiroug
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2011-12-01
Colección:	Frontiers in Cellular Neuroscience
Materias:	Pain temperature Receptor Trafficking ligand gated receptors P2X3 receptor
Acceso en línea:	http://journal.frontiersin.org/Journal/10.3389/fncel.2011.00027/full
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