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WDR33 alternative polyadenylation is dependent on stochastic poly(a) site usage and splicing efficiencies

Transcripts from the human WDR33 gene, which encodes a central component of the mRNA polyadenylation (PA) machinery, are subject to alternative polyadenylation (APA) within promoter-proximal introns/exons. This APA, which itself involves usage of multiple PA sites, results in the production of two n...

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Principais autores: Lizhi Liu, Takahiro Seimiya, James L. Manley
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:RNA Biology
Assuntos:
WDR33
CFIm25
alternative polyadenylation
innate immune responses
polyadenylation site
alternative splicing
Acesso em linha:https://www.tandfonline.com/doi/10.1080/15476286.2024.2408708
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