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Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans

Introduction Sphingolipid accumulation has been linked to obesity, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). A recent study showed that depletion of dihydroceramide desaturase-1 (DES-1) in adipose and/or liver tissue decreases ceramide-to-dihydroceramide ratios (ceramide/dihydro...

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Detaylı Bibliyografya
Asıl Yazarlar: Irene Esposito, Michael Roden, Christian Herder, Maria Apostolopoulou, Ruth Gordillo, Sofiya Gancheva, Klaus Strassburger, Matthias Schlensak, Philipp E Scherer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2020-12-01
Seri Bilgileri:BMJ Open Diabetes Research & Care
Online Erişim:https://drc.bmj.com/content/8/2/e001860.full
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