Comparative structural studies on Bovine papillomavirus E6 oncoproteins: Novel insights into viral infection and cell transformation from homology modeling and molecular dynamics simulations

Abstract Bovine papillomavirus (BPV) infects cattle cells worldwide, leading to hyperproliferative lesions and the potential development of cancer, driven by E5, E6, and E7 oncoproteins along with other cofactors. E6 oncoprotein binds experimentally to various proteins, primarily paxillin and MAML1,...

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Hlavní autoři:	Lucas Alexandre Barbosa de Oliveira Santos, Tales de Albuquerque Leite Feitosa, Marcus Vinicius de Aragão Batista
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Sociedade Brasileira de Genética 2024-08-01
Edice:	Genetics and Molecular Biology
Témata:	Bovine papillomavirus E6 oncoprotein molecular dynamics simulations CBP/p300 hMCM7.
On-line přístup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572024000400802&lng=en&tlng=en
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