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Crystal Structure of NADPH-Dependent Methylglyoxal Reductase Gre2 from <i>Candida Albicans</i>

Gre2 is a key enzyme in the methylglyoxal detoxification pathway; it uses NADPH or NADH as an electron donor to reduce the cytotoxic methylglyoxal to lactaldehyde. This enzyme is a member of the short-chain dehydrogenase/reductase (SDR) superfamily whose members catalyze this type of reaction with a...

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Autores principales: Giang Thu Nguyen, Shinae Kim, Hyeonseok Jin, Dong-Hyung Cho, Hang-Suk Chun, Woo-Keun Kim, Jeong Ho Chang
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2019-09-01
Colección:Crystals
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Acceso en línea:https://www.mdpi.com/2073-4352/9/9/471
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