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Effects of Ovarian Cancer Cell-Derived Extracellular Vesicles on The Proliferation and Expression Levels of Gdf-9, Amh, Igf1r and Foxl2 in Mouse Granulosa Cells

Objective: Granulosa cell tumor (GCT) is a sex cord-stromal rare malignancy; and is associated with infertility. Extracellular vesicles (EVs) are small secreted vesicles containing proteins, mRNA, and miRNA, therefore modulating signaling pathways potentially in recipient cells and in this way, they...

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Principais autores: Najme Nikdel, Javad Baharara, Saeed Zakerbostanabad, Maryam Tehranipour
Format: Artigo
Sprog:Inglês
Udgivet: Royan Institute (ACECR), Tehran 2024-11-01
Serier:Cell Journal
Fag:
extracellular vesicles
gene expression
granulosa cell tumor
ovarian cancer
proliferation
Online adgang:https://www.celljournal.org/article_722259_e63c757d1fa3ba92fcfca882d42ba366.pdf
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