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The LINC Between Mechanical Forces and Chromatin

The heart continually senses and responds to mechanical stimuli that balance cardiac structure and activity. Tensile forces, compressive forces, and shear stress are sensed by the different cardiac cell types and converted into signals instructing proper heart morphogenesis, postnatal growth, and fu...

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Principais autores: Olga Lityagina, Gergana Dobreva
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021-08-01
סדרה:Frontiers in Physiology
נושאים:
LINC complex
nuclear lamins
mechanotransduction
epigenetics
cardiovascular disease
cardiomyocyte
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fphys.2021.710809/full
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