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The proteomic landscape of the suprachiasmatic nucleus clock reveals large-scale coordination of key biological processes.

The suprachiasmatic nucleus (SCN) acts as the central clock to coordinate circadian oscillations in mammalian behavior, physiology and gene expression. Despite our knowledge of the circadian transcriptome of the SCN, how it impacts genome-wide protein expression is not well understood. Here, we inte...

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Autors principals: Cheng-Kang Chiang, Neel Mehta, Abhilasha Patel, Peng Zhang, Zhibin Ning, Janice Mayne, Warren Y L Sun, Hai-Ying M Cheng, Daniel Figeys
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2014-10-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC4199512?pdf=render
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