Abnormal neurovascular coupling induces glymphatic dysfunction in a mouse model of familial hemiplegic migraine type 2

Abstract Migraine is a prevalent primary headache disorder that significantly impairs daily life. Recent imaging studies have suggested that chronic migraine may be associated with changes in the function of the glymphatic system. Here, we describe altered cortical physiology in a genetic mouse mode...

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Bibliografische Detailangaben

Hauptverfasser:	Chenyang Duan, Shouyi Wu, Yuanxiang Li, KaiBo Zhang, Cunxin Lin, Yunqian Yao, Tianxiao Wang, Yonggang Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-11-01
Schriftenreihe:	The Journal of Headache and Pain
Schlagworte:	familial hemiplegic migraine type 2, glymphatic system, neurovascular coupling, perivascular spaces, astrocyte, migraine.
Online-Zugang:	https://doi.org/10.1186/s10194-025-02194-x
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