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Safety and efficacy of gefapixant, a novel drug for the treatment of chronic cough: A systematic review and meta-analysis of randomized controlled trials

AIM: We conducted this systematic review and meta-analysis to investigate the efficacy and safety of gefapixant, a novel P2X3 receptor antagonist, in patients with chronic cough. METHODS: We searched four databases for randomized controlled trials (RCTs). We assessed the cough frequency, severity, t...

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Principais autores: Ahmed Abu-Zaid, Aseel Khalid Aljaili, Amnah Althaqib, Fatima Adem, Doaa Ali Alhalal, Amena Faiq Almubarak, Saud Musaab Aldughaither, Sarah Ali Alghabban, Ghaidaa Alfaraj, Ahmed Taher Masoud, Nujud Abdullah Alsuhaibani
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2021-01-01
coleção:Annals of Thoracic Medicine
Assuntos:
af-219
chronic cough
gefapixant
mk-7264
p2x3 antagonist
Acesso em linha:http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2021;volume=16;issue=2;spage=127;epage=140;aulast=Abu-Zaid
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