Exploring the Chemical Properties and Medicinal Applications of Tetramethylthiocycloheptyne Sulfoximine Used in Strain-Promoted Azide–Alkyne Cycloaddition Reactions

The recently developed compound, tetramethylthiocycloheptyne sulfoximine (TMTHSI), has shown to be a promising strained alkyne for strain-promoted azide–alkyne cycloaddition (SPAAC), metal-free click chemistry. This research explores the properties of TMTHSI-based compounds via three aspects: (1) la...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Matt Timmers, Andi Kipper, Raphael Frey, Stef Notermans, Maksym Voievudskyi, Claire Wilson, Nina Hentzen, Michael Ringle, Clara Bovino, Bernhard Stump, Cristianne J. F. Rijcken, Tina Vermonden, Ingrid Dijkgraaf, Rob Liskamp
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	MDPI AG 2023-08-01
श्रृंखला:	Pharmaceuticals
विषय:	SPAAC click chemistry stability bio-orthogonal chemistry bioconjugation
ऑनलाइन पहुंच:	https://www.mdpi.com/1424-8247/16/8/1155
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