Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

Abstract Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread. Here, we show that Omicron exhibits increased infectivity in primary adult upper airway tissue relative to Delta. Using r...

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Autors principals:	Guoli Shi, Tiansheng Li, Kin Kui Lai, Reed F. Johnson, Jonathan W. Yewdell, Alex A. Compton
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-01-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-024-45075-8
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