People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells

Abstract CCR5 is the main HIV co-receptor. We aimed to (1) compare CCR5 expression on immune cells between people living with HIV (PLHIV) using combination antiretroviral therapy (cART) and HIV-uninfected controls, (2) relate CCR5 expression to viral reservoir size and (3) assess determinants of CCR...

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Principais autores:	Louise E. van Eekeren, Vasiliki Matzaraki, Zhenhua Zhang, Lisa van de Wijer, Marc J. T. Blaauw, Marien I. de Jonge, Linos Vandekerckhove, Wim Trypsteen, Leo A. B. Joosten, Mihai G. Netea, Quirijn de Mast, Hans J. P. M. Koenen, Yang Li, André J. A. M. van der Ven
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2022-07-01
Colecção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-022-15646-0
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