mRNA-LNP vaccination orchestrates systemic immunity to control human papillomavirus-positive head and neck squamous cell carcinoma

Messenger RNA (mRNA) vaccines have demonstrated significant potential in cancer immunotherapy by activating both innate and adaptive immunity. However, the detailed cellular and molecular dynamics underpinning these systemic immune responses remain incompletely understood. In this study, we characte...

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Detalhes bibliográficos

Principais autores:	Ke Qiu, Minzi Mao, Yao Song, Xing Duan, Yufang Rao, Lan Feng, Danni Cheng, Xiuli Shao, Yanling Liang, Chuanhuan Jiang, Hai Huang, Li Li, Yan Wang, Huifang Li, Mengli Zhu, Sisi Wu, Wei Xu, Geoffrey Liu, Jadwiga Jablonska, Stephan Lang, Shuaicheng Li, Fei Chen, Xingchen Peng, Yongbo Zheng, Haiyang Wang, Jun Liu, Yu Zhao, Xiangrong Song, Jianjun Ren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-12-01
Colecção:	Molecular Therapy: Nucleic Acids
Assuntos:	MT: Clinical Applications messenger RNA-lipid nanoparticle vaccination human papillomavirus-positive head and neck squamous cell carcinoma HNSCC systemic immune landscape interferon-stimulated gene
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253125003348
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