Distinct metabolic perturbations link liver steatosis and incident CVD in lean but not obese PWH

Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a key risk factor for cardiovascular disease (CVD), potentially driven by shared metabolic mechanisms. Metabolic perturbations associated with MASLD and CVD remain underexplored in people with HIV (PWH). Methods...

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Principais autores:	Louise E. van Eekeren, Nadira Vadaq, Marc J. T. Blaauw, Albert L. Groenendijk, Wilhelm A. J. W. Vos, Erni J. Nelwan, Annelies Verbon, Janneke E. Stalenhoef, Marvin A. H. Berrevoets, Jan van Lunzen, Mihai G. Netea, Gert Weijers, Niels P. Riksen, Joost H. W. Rutten, Quirijn de Mast, Eric T. T. L. Tjwa, Leo A. B. Joosten, André J. A. M. van der Ven
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-02-01
Series:	BMC Medicine
Assuntos:	HIV CVD MASLD Steatosis Fibrosis
Acceso en liña:	https://doi.org/10.1186/s12916-025-03914-5
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