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Silencing circ_0006104 inhibits the proliferation, activation and collagen synthesis by mouse cardiac fibroblasts through up-regulation of miR-370-3p

Objective To explore the function and mechanism of circular RNA 0006104 (circ_0006104) in regulating proliferation, activation and extracellular matrix (ECM) synthesis of cardiac fibroblasts (CFs) induced by angiotensin Ⅱ (Ang Ⅱ). Methods The primary CFs of neonatal mice were isolated and divided...

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Autor Principal: LI Ya-fei, DU Ying-qiang, WANG Ze-mu, ZHANG Jun
Formato: Artigo
Idioma:Chinês
Publicado: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-11-01
Series:Jichu yixue yu linchuang
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Acceso en liña:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-11-1667.pdf
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