DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes.
Antigenic variation in African trypanosomes requires monoallelic transcription and switching of variant surface glycoprotein (VSG) genes. The transcribed VSG, always flanked by '70 bp'-repeats and telomeric-repeats, is either replaced through DNA double-strand break (DSB) repair or transcriptionally...
שמור ב:
| Principais autores: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science (PLoS)
2013-03-01
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| סדרה: | PLoS Pathogens |
| גישה מקוונת: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23555264/?tool=EBI |
| תגים: |
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