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Hiding in Plain Sight: Formation and Function of Stress Granules During Microbial Infection of Mammalian Cells

Stress granule (SG) formation is a host cell response to stress-induced translational repression. SGs assemble with RNA-binding proteins and translationally silent mRNA. SGs have been demonstrated to be both inhibitory to viruses, as well as being subverted for viral roles. In contrast, the function...

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Bibliografiske detaljer
Principais autores: Alistair Tweedie, Tracy Nissan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-04-01
Serier:Frontiers in Molecular Biosciences
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2021.647884/full
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