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Modulation of the Acute Inflammatory Response Induced by the <i>Escherichia coli</i> Lipopolysaccharide through the Interaction of Pentoxifylline and Florfenicol in a Rabbit Model

Background: Experimental reports have demonstrated that florfenicol (FFC) exerts potent anti-inflammatory effects, improving survival in a murine endotoxemia model. Considering the anti-inflammatory and immunomodulatory properties of pentoxifylline (PTX) as an adjuvant to enhance the efficacy of ant...

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Principais autores: Victoria Cazanga, Cristina Palma, Tomás Casanova, Daniela Rojas, Karin Barrera, Cristhian Valenzuela, Aracelly Acevedo, Gabriel Ascui-Gac, Tamara Pérez-Jeldres, Rubén Pérez-Fernández
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-03-01
Series:Antibiotics
Assuntos:
anti-inflammatory
cytokines
antibiotics
pentoxifylline
florfenicol
drug interactions
Acceso en liña:https://www.mdpi.com/2079-6382/12/4/639
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