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NESmapper: accurate prediction of leucine-rich nuclear export signals using activity-based profiles.

The nuclear export of proteins is regulated largely through the exportin/CRM1 pathway, which involves the specific recognition of leucine-rich nuclear export signals (NESs) in the cargo proteins, and modulates nuclear-cytoplasmic protein shuttling by antagonizing the nuclear import activity mediated...

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Hlavní autoři: Shunichi Kosugi, Hiroshi Yanagawa, Ryohei Terauchi, Satoshi Tabata
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-09-01
Edice:PLoS Computational Biology
On-line přístup:http://europepmc.org/articles/PMC4168985?pdf=render
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