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Mathematical Model of Glucagon Kinetics for the Assessment of Insulin-Mediated Glucagon Inhibition During an Oral Glucose Tolerance Test

Glucagon is secreted from the pancreatic alpha cells and plays an important role in the maintenance of glucose homeostasis, by interacting with insulin. The plasma glucose levels determine whether glucagon secretion or insulin secretion is activated or inhibited. Despite its relevance, some aspects...

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Hauptverfasser: Micaela Morettini, Laura Burattini, Christian Göbl, Giovanni Pacini, Bo Ahrén, Andrea Tura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-03-01
Schriftenreihe:Frontiers in Endocrinology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fendo.2021.611147/full
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