Cognitive trajectories in early Parkinson's disease: A multimodal MRI study of brain structure and cognitive decline

Cognitive trajectories in Parkinson's disease (PD) exhibit substantial heterogeneity, ranging from long-term stability to rapid decline. The specific neural circuit dysfunctions underlying these distinct outcomes remain unclear. Utilizing magnetic resonance imaging (MRI) data from the Parkinson's Pr...

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Bibliografische Detailangaben

Hauptverfasser:	Chunmei Wen, Yi Xing, Hao Zhou, Jingzhe Li, Yukun Feng, Yinhao Xu, Haicun Shi, Xiao Hu, Junjie Zheng, Weiguo Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-07-01
Schriftenreihe:	Neurobiology of Disease
Schlagworte:	Parkinson's disease Cognitive decline Longitudinal MRI Gray matter volume Cerebello–thalamo–cortical circuit Free-water imaging
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S096999612600152X
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