Brain-gut-microbiota axis: a review on the bidirectional regulatory mechanisms between gut microbiota and brain and their disease interactions

ObjectiveTo synthesize current evidence on the bidirectional regulatory mechanisms of the Brain-Gut-Microbiota Axis (BGMA), its perturbation by external factors, and its clinical implications for neurodegenerative, psychiatric, metabolic, and gastrointestinal disorders.DesignNarrative review integra...

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Principais autores:	Hui Shen, Si Yun Wang, Yan Yan Zhao, Jia Lin Zhou, Jie Zhao, Wei Kai Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-03-01
Series:	Frontiers in Microbiology
Assuntos:	brain-gut-microbiota axis gut microbiota immune activation microbial metabolites neural pathways
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1768891/full
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