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A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistance

Abstract Background The epidermal growth factor receptor (EGFR) plays a significant role in vasculogenic mimicry (VM), a process by which aggressive cancer cells within hypoxic solid tumors form blood vessel-like structures independent of endothelial cells. Mostly attributed to cancer stem cells (CS...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Marie-Eve Roy, Alain Zgheib, Nicoletta Eliopoulos, Borhane Annabi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-08-01
Rangatū:BMC Cancer
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12885-025-14789-3
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